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Akheel Mohammad

City University Ajman, UAE

Title: Evaluation of clinico-pathological parameters and epidermal growth factor receptor status to create a mathematical model for prognosis of oral squamous cell carcinomas

Abstract

Oral Squamous Cell Carcinomas (OSCC) are the most common type of variant causing oral cancers, contributing for around 90%. The overall survival of these patients is below 50%. The postoperative Overall Survival (OS) has not improved over years much despite of advanced surgical techniques and invention of various anticancer drugs. There was always a requirement for a non-invasive molecular marker to predict the prognosis of these patients. The Epidermal Growth Factor (EGF) and their receptors are not only thought to play a critical but also an influential role in growth of the cell and differentiation in normal/ healthy tissues. This study put forward a proposed mathematical model by incorporating all important histopathological parameters to predict the prognosis of the patients. EGFR expression is one such important parameter to be considered to develop anti – EGFR agents to improve the OS of the patients.

Biography

TBA