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Basma Ezzat Mustafa AlAhmad
International Islamic University, MalaysiaTitle: Salivary IgA and early childhood caries
Abstract
Early Childhood Caries (ECC) prevalence was reported quite
high in many countries including Malaysia. Dental
caries is a predominant oral disease that results from chronic exposure to the
disparity of numerous factors. Saliva is the most significant essential factor of
dental caries, which provides physical and biological defensive mechanisms. Humoral immunologic response can regulate caries,
especially salivary secretory immunoglobulin A (s-IgA) which has
immunological control over dental caries and presumably prevents the adherence
of cariogenic microorganisms to the hard surfaces in
addition to the inhibition of the activity of glucosyl transferases. There is an association between caries
and the increased levels of sIgA, which may be due to many reasons like the
response to the mild exposition of dental caries as a form of a protective
mechanism of the body against caries attack, which will stimulate the production of sIgA that plays a role in oral
homeostasis. Still the relationship between sIgA and dental caries in controversial
and need further investigation.
Keywords:
Relation, Salivary Immunoglobulin A, Early Childhood Caries.
Biography
Basma Ezzat Mustafa has PhD in Clinical
Pharmacology, and MSc in clinical advanced laboratory sciences, and a
bachelor’s in pharmacy. She is the head of the basic medical sciences unit, and
head of the natural product research group in the faculty of dentistry at
International Islamic University Malaysia, she started working there in 2008 in
academic and research fields, she is doing her research in the field of
pharmacology, microbiology, immunology and different laboratory sciences in
relation to oral health in addition to several types of research in the field
of natural product, Dr. Basma has 25 years of experience in this field, during this period she manages to publish 5 books in addition to 50
publications. She
has been awarded the certificate of excellence in research and publication in
2019 at the kulliyyah level.
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